In this paper our aim is to examine whether research conducted on human participants with LSD-25 raises unique research ethical questions or demands particular concerns with regard to the design, conduct and follow-up of these studies, and should this be the case, explore and describe those issues. Our analysis is based on reviewing publications up to date which examine the clinical, research and other uses of LSD and those addressing ethical and methodological concerns of these applications, just as some historical (...) examinations of this subject. The first chapters of the paper give an overview regarding the history of LSD-research with human participants, healthy volunteers and patients alike. The remaining chapters have a focus on questions regarding the potential ethical issues of such human trials in the contemporary research ethics framework. We also consider briefly political and regulatory issues regarding this substance that possibly affect its clinical and research applications. (shrink)

We assess Cartwright's models for probabilistic causality, and in particular, her models for EPR-like experiments of quantum mechanics. We show that her models for the EPR are mathematically incorrect and physically implausible. Finally, we argue that her models are not adequate for EPR-phenomena, since they ignore modal and spatiotemporal aspects inherent in their setup.

We present the first comprehensive taxonomic revision and review the biology of the olingos, the endemic Neotropical procyonid genus Bassaricyon, based on most specimens available in museums, and with data derived from anatomy, morphometrics, mitochondrial and nuclear DNA, field observations, and geographic range modeling. Species of Bassaricyon are primarily forest-living, arboreal, nocturnal, frugivorous, and solitary, and have one young at a time. We demonstrate that four olingo species can be recognized, including a Central American species (Bassaricyon gabbii), lowland species with (...) eastern, cis-Andean (Bassaricyon alleni) and western, trans-Andean (Bassaricyon medius) distributions, and a species endemic to cloud forests in the Andes. The oldest evolutionary divergence in the genus is between this last species, endemic to the Andes of Colombia and Ecuador, and all other species, which occur in lower elevation habitats. Surprisingly, this Andean endemic species, which we call the Olinguito, has never been previously described; it represents a new species in the order Carnivora and is the smallest living member of the family Procyonidae. We report on the biology of this new species based on information from museum specimens, niche modeling, and fieldwork in western Ecuador, and describe four Olinguito subspecies based on morphological distinctions across different regions of the Northern Andes. (shrink)

Intertemporal choice involves deciding between smaller, sooner and larger, later rewards. People tend to prefer smaller rewards that are available earlier to larger rewards available later, a phenomenon referred to as temporal or delay discounting. Despite its ubiquity in human and non-human animals, temporal discounting is subject to considerable individual differences. Here, we provide a critical narrative review of this literature and make suggestions for future work. We conclude that temporal discounting is associated with key socio-economic and health-related variables. Regarding (...) personality, large-scale studies have found steeper temporal discounting to be associated with higher levels of self-reported impulsivity and extraversion; however, effect sizes are small. Temporal discounting correlates negatively with future-oriented cognitive styles and inhibitory control, again with small effect sizes. There are consistent associations between steeper temporal discounting and lower intelligence, with effect sizes exceeding those of personality or cognitive variables, although socio-demographic moderator variables may play a role. Neuroimaging evidence of brain structural and functional correlates is not yet consistent, neither with regard to areas nor directions of effects. Finally, following early candidate gene studies, recent Genome Wide Association Study (GWAS) approaches have revealed the molecular genetic architecture of temporal discounting to be more complex than initially thought. Overall, the study of individual differences in temporal discounting is a maturing field that has produced some replicable findings. Effect sizes are small-to-medium, necessitating future hypothesis-driven work that prioritizes large samples with adequate power calculations. More research is also needed regarding the neural origins of individual differences in temporal discounting as well as the mediating neural mechanisms of associations of temporal discounting with personality and cognitive variables. (shrink)

Papers presented at a Hungarian Academy of Sciences online workshop held on May 27, 2021.

The kernel of this volume is an English translation of Jan Łukasiewicz’s classic work on the concept of cause (1906). It is the starting point for analytical considerations on causality of two generations of philosophers belonging to the tradition of the Lvov-Warsaw School.

This research examined the role of thought suppression in the formation of mental blocks. In Experiment 1, participants were asked to generate a series of creative associates for two target words after initially suppressing a word that was semantically related to one of the two target words. Participants produced fewer responses, and experienced a greater sensation of being mentally blocked, when attempting to produce associates for the target word that was semantically related to the suppressed word. In Experiment 2, participants (...) either thought about or suppressed a series of words prior to completing a word fragment completion task. Each word either corresponded exactly to one of the word fragment solutions or resembled one of the solutions but was slightly different in its orthographic properties. Participants performed most poorly on the items for which they had initially suppressed negative primes. (shrink)

As narrative conceptions of selfhood have gained more acceptance within various disciplines including philosophy, psychology, and the cognitive sciences, so too have these conceptions been critically appraised. Chief among those who are suspicious of the overall viability of ‘narrative identity’ is the philosopher, Galen Strawson. In this paper, I develop five arguments underlying Strawson’s critique of narrative identity, and respond to each argument from the perspective of the hermeneutic phenomenology of Paul Ricœur. Though intuitive, I demonstrate that none of Strawson’s (...) arguments are cogent. The confrontation between these two figures highlights a deep conceptual disagreement about our epistemic access to the self, which has thus far gone unrecognized in the Anglo-American discussion, so that it raises a new problem for the metaphysics of personal identity. (shrink)

Name der Zeitschrift: Frühmittelalterliche Studien Jahrgang: 46 Heft: 1 Seiten: 99-156.

Stimulating innovation and growth in the so-called ‘creative economy’ is a current policy objective for national regulators. One policy lever traditionally applied to the creative sector is intellectual property, in particular the scope and term of protection offered by copyright. Opposition to expansion and further enclosure of the copyright public domain was previously articulated in terms of access to a commons of information. Since the Hargreaves Review of Intellectual Property in 2011, copyright reform in the UK context is increasingly framed (...) in the language of economics. This paper reviews two prevailing economic theories shaping how policy makers discuss the public domain in debates about IP reform: a welfare economics approach which weighs increases in producer and consumer surplus under different policy configurations and an economics of innovation approach which considers the value of the public domain as a reservoir of ideas for individuals and firms. I argue that economic definitions should be augmented by a consideration of the democratic requirement of access to information. The consequences of this re-figuration of the public domain for the public interest and access to information are discussed. (shrink)

Europe is the community of nations which, in the favorable conditions of a small yet extremely diversified continent, took over and developed the legacy of Greco-Roman civilization transformed and enriched by Christianity. Philosophy, theology, liturgy, religion, national culture and tradition are still manifestations of this heritage. Europe is not merely a region or geographical location. It is an idea that expresses cultural and social ideals. The nature of Europeanness is not defined by race or place but by freedom and culture (...) in the broad sense. Latin Europe created a sphere of civilization. Though ridden by contrasts and differences, not merely an organic unity was established but also a unity of a spiritual kind by accentuating and merging of values all Europeans have in common. This was also made possible by Christianity whose ethos came to pervade a multiplicity of socio-cultural phenomena. (shrink)

Contemporary public discourses are, despite the growing array of technologies and spaces for participation, becoming increasingly characterized by polarization – the formation of two distinct and r...

This research examined the role of thought suppression in the formation of mental blocks. In Experiment 1, participants were asked to generate a series of creative associates for two target words after initially suppressing a word that was semantically related to one of the two target words. Participants produced fewer responses, and experienced a greater sensation of being mentally blocked, when attempting to produce associates for the target word that was semantically related to the suppressed word. In Experiment 2, participants (...) either thought about or suppressed a series of words prior to completing a word fragment completion task. Each word either corresponded exactly to one of the word fragment solutions or resembled one of the solutions but was slightly different in its orthographic properties . Participants performed most poorly on the items for which they had initially suppressed negative primes. (shrink)

Fairness in machine learning (ML) is an ever-growing field of research due to the manifold potential for harm from algorithmic discrimination. To prevent such harm, a large body of literature develops new approaches to quantify fairness. Here, we investigate how one can divert the quantification of fairness by describing a practice we call “fairness hacking” for the purpose of shrouding unfairness in algorithms. This impacts end-users who rely on learning algorithms, as well as the broader community interested in fair AI (...) practices. We introduce two different categories of fairness hacking in reference to the established concept of p-hacking. The first category, intra-metric fairness hacking, describes the misuse of a particular metric by adding or removing sensitive attributes from the analysis. In this context, countermeasures that have been developed to prevent or reduce p-hacking can be applied to similarly prevent or reduce fairness hacking. The second category of fairness hacking is inter-metric fairness hacking. Inter-metric fairness hacking is the search for a specific fair metric with given attributes. We argue that countermeasures to prevent or reduce inter-metric fairness hacking are still in their infancy. Finally, we demonstrate both types of fairness hacking using real datasets. Our paper intends to serve as a guidance for discussions within the fair ML community to prevent or reduce the misuse of fairness metrics, and thus reduce overall harm from ML applications. (shrink)

What if language was an autonomous historical being? What if language’s use was not solely dependent on the intentions of the one who speaks? In this text I will test these provocative statements. Specifically, I will investigate whether language’s proclaimed historical independence can be traced in the usage of the concept of ‘secularisation’, and I will try to unveil the consequences of this operation.Contribution: Has Christianity abandoned the public stage in the ‘secularised’ and industrialised world? In this article I intend (...) to demonstrate that this is not the case. The continuous operative presence of Christianity in our socio-political language is used as the model to prove this argument. (shrink)

Scholar of religion Karl Kerényi’s last book, Dionysos, is a grand attempt at reinterpreting ζωη ( zoe ), the Greek concept of indestructible life, which he distinguishes from βίος (bios), finite life. In Kerényi’s view, the meaning and sensual experience of zoe was expressed in its richest form in the Cretan beginnings of the cult of Dionysos. The major characteristics of this cult, as Kerényi describes, were beyond the cultural, political, and sexual limits of the Christian interpretations of life and (...) nature. Searching for modern analogies to zoe , Kerényi explains the idea in relation to molecular biology’s minimum definition of life. Despite the fact that Kerényi’s book contains only minor references to contemporary philosophy, the philosophical consequences of his interpretations of Dionysos are not only radical but outline a notion of biopolitics far in advance of the mid- to late 20 th -century development of it. By the affirmation of indestructible life and animality , Kerényi proposes a new humanism that moves beyond the limits of Kantian anthropology and also takes a radically different perspective to that of Heidegger’s philosophy of being, or Agamben’s notion of biopolitics. According to Kerényi’s investigations, since this alternative humanism, which is based on the radical recognition of the individuality and diversity of life forms, was once possible in an earlier stage of human culture, it is possible to reanimate it in order to shape anew how zoe is understood and therefore lived. Our relation to nature can thereby undergo a Dionysian transvaluation and assign us new responsibilities as well as open up a new trajectory for the 21 st -century human. (shrink)

BackgroundRich in different kind of potent cells, embryos are used in modern regenerative medicine and research. Neurobiologists today are pushing the boundaries for what can be done with embryos existing in the transitory margins of medicine. Therefore, there is a growing need to develop conceptual frameworks for interpreting the transformative cultural, biological and technical processes involving these aborted, donated and marginal embryos. This article is a contribution to this development of frameworks.MethodsThis article examines different emotional, cognitive and discursive strategies used (...) by neurobiologists in a foetal cell transplantation trial in Parkinson’s disease research, using cells harvested from aborted embryos. Two interviews were analysed in the light of former observations in the processing laboratories, using the anthropologist Mary Douglas’s concept of pollution behaviour and the linguist, philosopher, psychoanalyst and feminist Julia Kristeva’s concept of the abjective to explain and make sense of the findings.ResultsThe findings indicate that the labour performed by the researchers in the trial work involves transforming the foetal material practically, as well as culturally, from trash to treasure. The transformation process contains different phases, and in the interview material we observed that the foetal material or cells were considered objects, subjects or rejected as abject by the researchers handling them, depending on what phase of process or practice they referred to or had experience of. As demonstrated in the analysis, it is the human origin of the cell that makes it abjective and activates pollution discourse, when the researchers talk of their practice.ConclusionsThe marginal and ambiguous status of the embryo that emerges in the accounts turns the scientists handling foetal cells into liminal characters in modern medicine. Focusing on how practical as well as emotional and cultural strategies and rationalizations of the researchers emerge in interview accounts, this study adds insights on the rationale of practically procuring, transforming and utilizing the foetal material to the already existing studies focused on the donations. We also discuss why the use and refinement of a tissue, around which there is practical consensus but cultural ambiguity, deserves further investigation. (shrink)

It is argued that the assignment of truth values to future contingents is threatened not by a tensed metaphysics but by a temporally “local” notion of truth, i.e., by the assumption that whatever is true at a given time needs to be grounded in what exists at that time. If this assumption is accepted, tensed and tenseless metaphysics are equally vulnerable; if it is rejected, both can accommodate true future contingents. This means that semantic decisions are largely independent of metaphysical (...) considerations. The work of Correia and Rosenkranz (2018) is a clear example of how the tensed metaphysics of the growing block can incorporate true future contingents. Two potential worries are discussed in the context of their work: (a) that their grounding strategy overgeneralizes and admits true counterfactual contingents; and (b) that the growing block theory lacks sufficient resources to distinguish the unique possible future course of events that is relevant for the grounding of future contingents. (shrink)

In this paper I present two new strategies for inconsistencyadaptive logics: the reliable sufficient information strategy of ACLuN3 andthe minimally abnormal sufficient information strategy of ACLuN4. I giveproof theory and semantics for both ACLuN3 and ACLuN4. I also compare them with the well-known inconsistency-adaptive logics ACLuN1 andACLuN2.

Der vorliegende Aufsatz berührt zwei bis heute nur im geringen Maße erforschte und thematisierte Probleme der Übersetzungstheorie. Es geht hier vor allem um eine möglichst kompakte Darstellung einer Diskussion über solche Begriffe wie Kultur, Fremderfahrung, Fremdverstehen, oder Alienation und Alterität. Der wissenschaft1iche Diskurs, in welchem beide der erwähnten Themen immer wieder zur Sprache kommen, gewinnt heutzutage für eine einheitliche Beschreibung der literarischen Übersetzung einen interessanten, obwohl methodologisch noch nicht ganz sicheren Boden. In erster Linie liegt das Problem des Kulturphänomens auf (...) dem Gebiet der Übersetzung in der Art und Weise seiner Analyse. Wie funktioniert der fremde und fremdsprachige Kontext in der kommunikativen Situation der Übersetzung, was doch eine Begegnung der Kulturen bedeutet? Wie ist es mit den Artefakten der fremden Kultur, Kunst und Literatur umzugehen? Welche Sprache soll die Aufgabe der Beschreibung leisten? Es werden hier nur die wichtigsten Fragen einer kulturspezifisch orientierten Übersetzungswissenchaft aufgezahlt. Ein Versuch, nur auf diese Fragen eine allgemeine Antwort zu erteilen, würde den Rahmen jenes kurzen Aufsatzes mit großter Sicherheit sprengen. Nichtsdestotrotz lohnt es sich über die immer aktuellen Quästionen der literarischen Übersetzung ein paar Worte zu sagen. Ich heiter, meine kurze und notwendigerweise oberflächliche Arbeit möge doch als ein guter Ansatz zum Thema: Kultur in der literarischen Übersetzung dienen. (shrink)

This paper discusses the problem of inconsistencies in the metaphorical conceptualizations of time that involve motion within the framework of conceptual metaphor theory (CMT). It demonstrates that the TIME AS A PURSUER metaphor contrasts with the reverse variant TIME AS AN OBJECT OF PURSUIT, just as the MOVING TIME metaphor contrasts with the MOVING OBSERVER variant. Such metaphorical conceptualizations of time functioning as pairs of minimally differing variants based on Figure-Ground reversal are, strictly speaking, inconsistent with one another. Looking at (...) these inconsistencies from a wider perspective suggests that time may belong to a separate category of conceptual phenomena. This paper puts forward a proposal to approach time from the perspective of “phenomena of the third kind”, which according to Keller’s thesis include conceptual establishments resulting from human cognition, but not of human design. (shrink)

Obcy Inny. Analiza przypadków. 2017, ed. Małgorzata Karwatowska, Robert Litwiński, AdamSiwiec. Wydawnictwo UMCS, Lublin.Obcy/Inny, Propozycje aplikacji pojęciowych. 2018, ed. M. Karwatowska, R. Litwiński, A. Siwiec,Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej, Lublin.

The study focuses on the ethical aspects of decision-making by national elites in the context of the thinking of Ján Kollár (1793–1852) and Ľudovít Štúr (1815–1856) on the issue of Slavism. Attention is paid to the issue of responsibility for preserving the greatness and unity of the nation in the context of the formation of national identity and individuality. The concepts of the mentioned authors had an impact on the cultural-civilizational orientation of Slovak elites with an emphasis on the role (...) of moral obligations in shaping the value orientation of the nation. In this context, the analysis focuses on the works Reciprocity between the various tribes and dialects of the Slavic nation and Slavdom and the world of the future, which, at the same time, represent alternative concepts of the cultural and political orientation of the Slavs. The study simultaneously analyses these concepts as alternative programs of cultural and political development of national identity, as well as concepts aimed at humanist and political goals. (shrink)

In 1968 the authors of the so-called Harvard Report, proposed the recognition of an irreversible coma as a new criterion for death. The proposal was accepted by the medical, legal, religious and political circles in spite of the lack of any explanation why the irreversible coma combined with the absence of brainstem reflexes, including the respiratory reflex might be equated to death. Such an explanation was formulated in the President’s Commission Report published in 1981. This document stated, that the brain (...) is the central integrator of the body, therefore the destruction of the brain results in the lack of that integration and the death of the organism. Therefore, according to that document, the so-called “brain dead” patients are really, biologically dead; strictly speaking they are not any more biological organisms but collections of organs and tissues. Their death was masked by the use of the medical equipment, but it was a real, biological death. Thus, the explanation given by the President’s Commission Report constituted a biological rationale for the new concept of death, known as “brain death.” However, after the long discussion, this rationale was refuted because of the evidence given by many medical authorities, that the bodies of the “brain dead” and “brainstem dead” patients are alive. In the context of the discussion about the neurological criteria for death, some authors follow the idea of Plato, that human being is the soul or mind, and the body does not belong to the human essence. Therefore, the loss of consciousness, which may be identified with the mind, constitutes the loss of personhood and may be interpreted as human death. The other group stresses the Aristotelian and Thomistic concept that the body belongs to the essence of every living creature, including human. Therefore, as long as the body is alive, the human being is alive and we cannot call the given patient dead even if he is deeply comatose. Moreover, in spite of the opinions dominating in the mass-media, these patients should be considered not only alive but also may be conscious to some degree and their state can be reversible. Their brains are lacking the electrical functions, but the neuronal tissue is alive and that state is reversible for at least first 48 hours since the onset of coma; this phenomenon is called “global ischemic penumbra” and is responsible for the regularly happening events interpreted as miracles, when some of the “brain dead” or “brainstem dead” patients turn to be alive and come back to normal life. Therefore, the neurological criteria of death are still lacking generally accepted scientific basis and should not be used in medicine and in the legal systems as a basis for diagnosing comatose/having no brainstem reflexes/apneic patients dead. (shrink)

The dialectical-theological origins of the politically- and ethically-charged concept of alterity are well-known within the philosophy of religion. Intellectual histories of this concept tie it too exclusively to the notion of distance or διάστασις in Karl Barth’s early Römerbrief, however, and so miss Barth’s Trinitarian reinterpretation of God’s otherness in his later work. Taking as my hermeneutical key a cipher, the ‘sign of Jonah,’ that emerges in Church Dogmatics IV/1, I show that Barth’s mature doctrines of temporality and filiation understand (...) alterity as a moment of divine life. Jesus’ agony in the garden of Gethsemane marks the climax of Barth’s self-reinterpretation: world history inheres within the Christological situation of paternal abandonment. The political-theological conclusions Barth draws from the ‘sign of Jonah’ dovetail with alterity discourses’ antitotalitarian aspirations but suggest that these aspirations’ structural coherence rest on the magisterial Reformers’ Christological and ecclesiological commitments. (shrink)

Let J be any proper ideal of subsets of the real line R which contains all finite subsets of R. We define an ideal J * ∣B as follows: X ∈ J * ∣B if there exists a Borel set $B \subset R \times R$ such that $X \subset B$ and for any x ∈ R we have $\{y \in R: \langle x,y\rangle \in B\} \in \mathscr{J}$ . We show that there exists a family $\mathscr{A} \subset \mathscr{J}^\ast\mid\mathscr{B}$ of power ω (...) 1 such that $\bigcup\mathscr{A} \not\in \mathscr{J}^\ast\mid\mathscr{B}$ . In the last section we investigate properties of ideals of Lebesgue measure zero sets and meager sets in Cohen extensions of models of set theory. (shrink)